Wayne Manor was the ancestral home of Bruce Wayne. He was raised there from birth, first by his father, Thomas, and mother, Martha, and after their deaths, by his butler and surrogate father, Alfred Pennyworth.
Several hidden entrances led to the Batcave, which rested underground and was beneath Wayne Manor.
Vicki Vale and Alexander Knox attended a benefit at Wayne Manor, where Bruce was taken by Vicki's charm. Bruce left the benefit to stop a raiding at Axis Chemicals as Batman. Bruce slept with Vicki for a night. Bruce tells Vicki that "he is going out of town for a few days", before leaving.
Dick Grayson discovered an entrance to the Batcave that was concealed behind a silverware storage cupboard. The Riddler left a riddle on the manor's front gates. Later, Two-Face started a raid at the manor as Riddler wreaks havoc in the Batcave.
Bruce and Dick often have a relationship arguments over stopping Mr. Freeze and Poison Ivy. Barbara Wilson, Alfred's niece, made a surprise visit and was invited to stay at Wayne Manor until she returned to college back in England.