Wayne Kirkpatrick (born c. 1961) is an American songwriter and musician born in Baton Rouge, Louisiana but now lives in Nashville, Tennessee. He graduated from Baton Rouge Magnet High School in 1979. His younger brother is American screenwriter and director Karey Kirkpatrick.
Around 2010, Wayne and his brother Karey began working on the musical Something Rotten!. In 2015, they were nominated for a Tony Award for Best Original Score (Music and/or Lyrics) Written for the Theatre (along with many other awards), while Karey was also nominated for a Tony Award for Best Book of a Musical with British author John O'Farrell.
In 2018 he co-wrote the songs to Smallfoot with his brother Karey Kirkpatrick.