Mojo, tired of a string of failures, decides to try and find the girls' weaknesses by taking their prized toys and using a machine to allow them to talk. However, getting the toys to spill their deep secrets turns out to be harder than he thought.
Coincidentally, the Girls' snuggle toys make an appearance during the intro.
Monsieur Ducky is making its first appearance in this episode. In "Secret Swapper of Doom" it has been mentioned by Buttercup.
This episode marks Octi's first speaking role unlike its 1998 counterpart in the original series.
Technically in "Octi Evil", Bubbles believes Octi can talk, but it turned out it was HIM who manipulated and took over Octi.
There's a running gag when Mojo has suffered numerous defeats from the Girls is similar in "The Rowdyruff Boys" from an episode of the original series.
This episode shows the second time of Bubbles' pimento allergy. The first being "Power Up Puff".
Blossom reveals in her flashback that she got President Dinosaur as a Christmas present.
Like the Girls, Mojo is also shown to have a snuggle toy at the end of the episode.
Gwen from the episode "Viral Spiral" makes a cameo appearance in the coffee shop.
Running gag: Hairydactyl keeps showing up attacking Blossom while she easily takes him down.
Season 1:Monkey See, Doggie Do • Mommy Fearest • Insect Inside • Powerpuff Bluff • Octi Evil • Geshundfight • Buttercrush • Fuzzy Logic • Boogie Frights • Abracadaver • Telephonies • Tough Love • Major Competition • Mr. Mojo's Rising • Paste Makes Waste • Ice Sore • Bubblevicious • The Bare Facts • Cat Man Do • Impeach Fuzz • Just Another Manic Mojo • Mime for a Change • The Rowdyruff Boys • Uh Oh Dynamo Season 2:Stuck Up, Up and Away • Schoolhouse Rocked • Collect Her • Supper Villain • Birthday Bash • Too Pooped to Puff • Beat Your Greens • Down n' Dirty • Dream Scheme • You Snooze You Lose • Slave the Day • Los Dos Mojos • A Very Special Blossom • Daylight Savings • Mo Job • Pet Feud • Imaginary Fiend • Cootie Gras • The Powerpuff Girls Best Rainy Day Adventure Ever • Just Desserts • Twisted Sister • Cover Up • Speed Demon • Mojo Jonesin • Something's a Ms. • Slumbering with the Enemy Season 3:Fallen Arches • The Mane Event • Town and Out • Child Fearing • Criss Cross Crisis • Bubblevision • Bought and Scold • Gettin' Twiggy With It • Cop Out • Three Girls and a Monster • Monkey See, Doggy Two • Jewel of the Aisle • Super Zeroes • Candy Is Dandy • Catastrophe • Hot Air Buffoon • Ploys R' Us • The Headsucker's Moxy • Equal Fights • Powerprof. • Moral Decay • Meet the Beat Alls • Helter Shelter • Power Lunch Season 4:Film Flam • All Chalked Up • Get Back Jojo • Him Diddle Riddle • Super Friends • Members Only • Nano of the North • Stray Bullet • Forced Kin • Knock It Off Season 5:Keen on Keane • Not So Awesome Blossom • Power-Noia • Monstra-City • Shut the Pup Up • Toast of the Town • Divide and Conquer • Burglar Alarmed • Shotgun Wedding • Save Mojo • Substitute Creature • The Boys Are Back in Town • See Me, Feel Me, Gnomey • Pee Pee G's • Boy Toys • Seed No Evil • The City of Clipsville • Lying Around the House • Bubble Boy • A Documentary • Girls Gone Mild • Curses • Bang for Your Buck • Silent Treatment • Sweet 'n' Sour Season 6:Prime Mates • Coupe D'Etat • Makes Zen to Me • Say Uncle • Reeking Havoc • Live & Let Dynamo • Mo' Linguish • Oops, I Did It Again • A Made Up Story • Little Miss Interprets • Night Mayor • Custody Battle • The City of Nutsville • Aspirations • That's Not My Baby • Simian Says • Sun Scream • The City of Frownsville • West in Pieces • Crazy Mixed Up Puffs • Mizzen in Action • Roughing It Up • What's the Big Idea? • Nuthin' Special • Neighbor Hood • I See a Funny Cartoon in Your Future • Octi-Gone Reboot: