On one of the finest days in Townsville, ThePowerpuffGirls are always helping the townspeople with everything, like rescuing the cat from a tree, being on class on time, helping the Mayor open the pickle jar, and helping Professor Utonium with his science project. While everyone falls asleep during nighttime, HIM gets tired of the Powerpuff Girls helping everything, so he uses his scent to turn the people against the girls.
The next day, it happens again. Bubbles attempts to rescue the cat from the tree again, but the cat angrily refuses. The old lady is also angry as well and Bubbles, (who rescued the cat and is shredded in pain) does not like it. The old lady beats the girls with a cane and once the school bell has rung, the girls make it on time, only for their teacher, Ms. Keane, who marks the girls tardy. This triggers a kid named Billy who throws a paper ball at Bubbles and when she tried to tell that to Ms. Keane, She tells her students to throw everything at the girls. Then the hotline buzzes and the girls take off and arrive at the Mayor's office. When Blossom tries to open the pickle jar again, the Mayor sends a S.W.A.T Team to corner the girls. After that, the Mayor declares that Ms. Bellum should fire first. Blossom, Bubbles, and Buttercup leave, while Buttercup complains this has been a rough day, much to the Narrator's Irritation. They head to the Professor's Lab and they try to find out the situation, only for Professor Utonium himself who tries to catch the girls in anger. The girls manage to escape the front door, only for the townspeople to appear and get ready to beat up the girls (they now have red glowing eyes). HIM reveals himself and his evil plan and orders the townspeople to attack the Girls. At first, they don't even try to fight, but soon realize they have to fight their friends and loved ones to revert them back to their normal selves. They manage to do so and warn HIM that if he tries something like this again, he will regret it. HIM assures them that he doesn't give "repeat performances", and disappears into the sky.
At the hospital, the Girls explain the situation to the townspeople, and apologize, saying "It hurt us a lot more than it hurt you!", although their now-injured friends and loved ones agree to the contrary. The Narrator, who was also part of the pummeling, says they forgive the Girls, and calls for his sponge bath.
The Narrator calls Townsville "The City of Brotherly Love", or should I say "Sisterly Love". This is a reference to the nickname of Philadelphia, Pennsylvania. This might be due to the fact that Philadelphia has its reputation of being known as "The City of Brotherly Love".
This episode so far is the most to have its music reused in the next episodes.
At the end of the episode, the townspeople all say "Well now, we wouldn't say that!" This is a reference to The Great Gildersleeve, particularly Richard Q. Peavey's catchphrase "Well now, I wouldn't say that!"
Season 1:Monkey See, Doggie Do • Mommy Fearest • Insect Inside • Powerpuff Bluff • Octi Evil • Geshundfight • Buttercrush • Fuzzy Logic • Boogie Frights • Abracadaver • Telephonies • Tough Love • Major Competition • Mr. Mojo's Rising • Paste Makes Waste • Ice Sore • Bubblevicious • The Bare Facts • Cat Man Do • Impeach Fuzz • Just Another Manic Mojo • Mime for a Change • The Rowdyruff Boys • Uh Oh Dynamo Season 2:Stuck Up, Up and Away • Schoolhouse Rocked • Collect Her • Supper Villain • Birthday Bash • Too Pooped to Puff • Beat Your Greens • Down n' Dirty • Dream Scheme • You Snooze You Lose • Slave the Day • Los Dos Mojos • A Very Special Blossom • Daylight Savings • Mo Job • Pet Feud • Imaginary Fiend • Cootie Gras • The Powerpuff Girls Best Rainy Day Adventure Ever • Just Desserts • Twisted Sister • Cover Up • Speed Demon • Mojo Jonesin • Something's a Ms. • Slumbering with the Enemy Season 3:Fallen Arches • The Mane Event • Town and Out • Child Fearing • Criss Cross Crisis • Bubblevision • Bought and Scold • Gettin' Twiggy With It • Cop Out • Three Girls and a Monster • Monkey See, Doggy Two • Jewel of the Aisle • Super Zeroes • Candy Is Dandy • Catastrophe • Hot Air Buffoon • Ploys R' Us • The Headsucker's Moxy • Equal Fights • Powerprof. • Moral Decay • Meet the Beat Alls • Helter Shelter • Power Lunch Season 4:Film Flam • All Chalked Up • Get Back Jojo • Him Diddle Riddle • Super Friends • Members Only • Nano of the North • Stray Bullet • Forced Kin • Knock It Off Season 5:Keen on Keane • Not So Awesome Blossom • Power-Noia • Monstra-City • Shut the Pup Up • Toast of the Town • Divide and Conquer • Burglar Alarmed • Shotgun Wedding • Save Mojo • Substitute Creature • The Boys Are Back in Town • See Me, Feel Me, Gnomey • Pee Pee G's • Boy Toys • Seed No Evil • The City of Clipsville • Lying Around the House • Bubble Boy • A Documentary • Girls Gone Mild • Curses • Bang for Your Buck • Silent Treatment • Sweet 'n' Sour Season 6:Prime Mates • Coupe D'Etat • Makes Zen to Me • Say Uncle • Reeking Havoc • Live & Let Dynamo • Mo' Linguish • Oops, I Did It Again • A Made Up Story • Little Miss Interprets • Night Mayor • Custody Battle • The City of Nutsville • Aspirations • That's Not My Baby • Simian Says • Sun Scream • The City of Frownsville • West in Pieces • Crazy Mixed Up Puffs • Mizzen in Action • Roughing It Up • What's the Big Idea? • Nuthin' Special • Neighbor Hood • I See a Funny Cartoon in Your Future • Octi-Gone Reboot:
