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Space Ghost Coast to Coast is an American animated parody talk show, created by Mike Lazzo and hosted by the 1960s Hanna-Barbera cartoon character Space Ghost.

Space Ghost Coast to Coast was considered to be the first fully produced Cartoon Network original series, and premiered on April 15, 1994. The first two seasons were presented as a serious talk show with subdued jokes, while the later seasons relied more on surrealism, non-sequiturs, and parodies. In 2001, it moved to the network's late night television block Adult Swim.

A revival ran on GameTap from 2006 to 2008.

Plot[]

Space Ghost Coast to Coast was known for inspiring the series Cartoon Planet, The Brak Show, Sealab 2021, Aqua Teen Hunger Force, Harvey Birdman, Attorney At Law, Perfect Hair Forever and The Eric Andre Show. Space Ghost Coast to Coast used the talk show format as its template, but subverted it regularly. Various celebrities appeared on the show as guests. They were shown on a TV screen next to Space Ghost's desk, and unlike the characters, they were not animated.

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