It's night time in the city of Townsville, and every one is sleeping, getting ready for tomorrow. However, someone isn't sleeping, and that someone has cleverly stolen a repaired dog-headed bust, along with a pair of rubies, from the Townsville Museum. The next day, the girls investigate the crime scene, and just when they thought they couldn't find any clues, the stolen rubies (the Anubial Jewels) would come to qualify. Just then, the girls realize that this may be a repeat incident and speed off to find a trail.
The girls think this is weird, then they look to see the entire city once again populated by dogs. In time, the girls come to conclude that Mojo Jojo is behind this and are on his tail almost instantly. Rather than beat him up immediately, they chastise him for his stupidity, recycling an old plot in hopes of a more desirable outcome. Mojo has a plan, however; he reviewed his plan and its faults as seen in the last episode he used this plan (Monkey See, Doggie Do) courtesy of conveniently placed televisions and cameras to provide him worldwide video surveillance. He reached the conclusion that his plan fell apart when he turned the girls into dogs and they then bit him, so he decides against turning the girls into dogs and instead equips himself with a steel plate to protect him from being bitten. Confident in his victory he asks what the girls will dare hope to defeat him now, but they still whoop him as is classical. Mojo once again drops the head and the curse is lifted as he takes on a dog form. Mojo 'Dog' is back in the pound with a 'very' large bulldog.
This is the last of the four episodes in season three that Genndy Tartakovsky directed. It's also the last episode crediting him as director.
The beginning of this episode, all the way until the girls had investigated the museum, uses exactly the same clip as "Monkey See, Doggie Do", revealing that this episode was almost a remake of the mentioned episode and Craig McCracken and the animators thought that this episode was really easy for them to do. Later on, more clips from this episode are shown on Mojo's TV.
This episode takes place a few days after the events of the episode "Monkey See, Doggie Do".
The animated outro in this episode is nearly the same as in "A Very Special Blossom", but the outro proceeds as normal, the hearts are presented over a dark red background, and the girls are seen smiling and are in their normal poses.
In this episode, it is implied that Mojo has cameras all over the world since his TV seems to be able to show anything that happened anywhere at any time at all, much like HIM's TV or his magical floating screens in later seasons.
Running gag: Mojo Jojo saying "The dogs... the biting... the dropping". The Narrator copies that end of this episode as "The day... the saving... the girls".
Neither this episode nor its predecessor explain how Mojo goes back to normal.
The bulldog is a resemblance to Chopper from Yakky Doodle.
Season 1:Monkey See, Doggie Do • Mommy Fearest • Insect Inside • Powerpuff Bluff • Octi Evil • Geshundfight • Buttercrush • Fuzzy Logic • Boogie Frights • Abracadaver • Telephonies • Tough Love • Major Competition • Mr. Mojo's Rising • Paste Makes Waste • Ice Sore • Bubblevicious • The Bare Facts • Cat Man Do • Impeach Fuzz • Just Another Manic Mojo • Mime for a Change • The Rowdyruff Boys • Uh Oh Dynamo Season 2:Stuck Up, Up and Away • Schoolhouse Rocked • Collect Her • Supper Villain • Birthday Bash • Too Pooped to Puff • Beat Your Greens • Down n' Dirty • Dream Scheme • You Snooze You Lose • Slave the Day • Los Dos Mojos • A Very Special Blossom • Daylight Savings • Mo Job • Pet Feud • Imaginary Fiend • Cootie Gras • The Powerpuff Girls Best Rainy Day Adventure Ever • Just Desserts • Twisted Sister • Cover Up • Speed Demon • Mojo Jonesin • Something's a Ms. • Slumbering with the Enemy Season 3:Fallen Arches • The Mane Event • Town and Out • Child Fearing • Criss Cross Crisis • Bubblevision • Bought and Scold • Gettin' Twiggy With It • Cop Out • Three Girls and a Monster • Monkey See, Doggy Two • Jewel of the Aisle • Super Zeroes • Candy Is Dandy • Catastrophe • Hot Air Buffoon • Ploys R' Us • The Headsucker's Moxy • Equal Fights • Powerprof. • Moral Decay • Meet the Beat Alls • Helter Shelter • Power Lunch Season 4:Film Flam • All Chalked Up • Get Back Jojo • Him Diddle Riddle • Super Friends • Members Only • Nano of the North • Stray Bullet • Forced Kin • Knock It Off Season 5:Keen on Keane • Not So Awesome Blossom • Power-Noia • Monstra-City • Shut the Pup Up • Toast of the Town • Divide and Conquer • Burglar Alarmed • Shotgun Wedding • Save Mojo • Substitute Creature • The Boys Are Back in Town • See Me, Feel Me, Gnomey • Pee Pee G's • Boy Toys • Seed No Evil • The City of Clipsville • Lying Around the House • Bubble Boy • A Documentary • Girls Gone Mild • Curses • Bang for Your Buck • Silent Treatment • Sweet 'n' Sour Season 6:Prime Mates • Coupe D'Etat • Makes Zen to Me • Say Uncle • Reeking Havoc • Live & Let Dynamo • Mo' Linguish • Oops, I Did It Again • A Made Up Story • Little Miss Interprets • Night Mayor • Custody Battle • The City of Nutsville • Aspirations • That's Not My Baby • Simian Says • Sun Scream • The City of Frownsville • West in Pieces • Crazy Mixed Up Puffs • Mizzen in Action • Roughing It Up • What's the Big Idea? • Nuthin' Special • Neighbor Hood • I See a Funny Cartoon in Your Future • Octi-Gone Reboot: