Characters who are the antagonists. Furthermore, not all antagonists are villains because they are normally bad guys, neutral characters, or redeemed villains depending in the story.
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A
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- Agent Smith
- Alexander Luthor Jr.
- Alvin Marsh
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- Arjen Rudd
- Arnold Royalton
- Arnold the Pit Bull
- Arthur Slugworth
B
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- Bane (The Matrix)
- Barkis Bittern
- Bartemius Crouch Jr.
- Beaky Buzzard
- Beetlejuice (character)
- Bellatrix Lestrange
- Berkely Beetle
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- Blackfire
- Bluebeard
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- Bowers Gang
- Brain (Pinky and the Brain)
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- Burmese Tiger
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C
- Candle Jack
- Cannonball Taylor
- Captain Montecero
- Casbah Rabbit
- Casper Caveman
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- Central Park Rangers
- Chad Dickson
- Charmcaster
- Cheswick
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- Clara Dalrymple
- Clyde Northcutt
- CM Punkrock
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- Cornelius Fudge
- Cosmo Spacely
- Counselor Dish
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- Count Grisham
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- Count Spankulot
- Wile E. Coyote
- Credence Barebone
- Cree Lincoln
- Cruncher Block
- Cujo
- Cypher
D
- Danny Jacobs
- Dark Kat
- Dick Dastardly
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- Death Eaters
- Delbert Grady
- Delightful Children From Down the Lane
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- Devil Dog
- Devlin Levin
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- Diana (Lights Out)
- Dick Hardly
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- Dolores Umbridge
- Duncan Douglas
- Dr. Applecheek
- Dr. Evil
- Dr. Greed
- Dr. Loveless
- Dr. Scratchansniff
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- Draco Malfoy
- Drake
- Duchess
E
F
- Father (Codename: Kids Next Door)
- Fire crab
- Flanigan
- Frankie Lombardo
- Freddy Krueger
- Elmer Fudd
- Fulton Greenway
- Furrball
- Fuzzy Lumpkins
G
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- The Gangreen Gang
- Gellert Grindelwald
- General Parvo
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- George Hatton
- George Hedare
- Georgia (Duck Dodgers)
- Gimbel's Santa
- Gollum
- Gossamer
- Grant Frost
- Gregory Goyle
- Gretta Keene
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- Grover Dill
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- Grundel Toad
H
- Harley Quinn
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- Hector the Bulldog
- Henry Bowers
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- Hugo the Abominable Snowman
- Hunter (Storks)
I
J
- J.P. Cubish
- Jack Joshua
- Jack Torrance
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- James Bennet
- James Nixon McGarfield
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- Waylon Jeepers
- Joker
- Justin Cavallero
K
L
- L.B. Mammoth
- Laura Limpin
- Lex Luthor
- Lickboot
- Gilderoy Lockhart
- Lord Business
- Lord Garmadon
- Lord Voldemort
- Lucius Malfoy
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- Léon Rom
M
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- Major Heinrich Strasser
- Man with Flamethrower
- Mandark
- Marble Henry
- The Martin Brothers
- Marvin the Martian
- Master Little
- Master of Games
- Maudeline and Finis Everglot
- Max (Cats Don't Dance)
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- Mayor Phlegmming
- Mayor R. Brown
- Mega Mom & Destructo Dad
- Meowrice
- Meowthra
- Metal Beak
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- Miss Almira Gulch
- Miss Minchin
- Mojo Jojo
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- Mouse King
- Mouse Queen
- Mozo and Gringo
- Mr. Boss
- Mr. Chairman
- Mr. Cogswell
- Mr. Crazy Person
- Mr. Fizz
- Mr. Frum
- Mr. Mole
- Mr. Pickles (character)
- Mr. Swackhammer
- Mr. Tinkles
- Mr. Vice Roy
- Mrs. Medlock
- Mrs. Toad
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- Muttley
N
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